Treatment of Photomelanosis and Photo Tanning

Co-creation from stakeholders and community input

Stop the guesswork! Our prototype concepts come from science/evidence-based research conducted by our researchers, sensory research from panellists, competitors and product market research, and inputs from consumers through focus groups, interviews, regional-focused consumer journey mapping, and many more. Get information that allows you to make crystal clear decisions.

Ingredient Focus

We build our prototype with the use of real, clean, fresh and authentic ingredients (such as free from an allergen, no pesticide/chemicals/toxins, non-GMO, gluten-free, organic, vegetarian, gluten-free, and minimally processed) without compromising on sensory appeal. Our prototype, built by our formulation scientists, will ensure to present 'NO LIST' includes Parabens, Sulfate, Petroleum, Phthalates, mineral oil, talc, BHA, formaldehyde, paraffin, silicone and more

Clean Label

No complex labelling of disgusting ingredients in the formulation. We offer clean labelling with maximum transparency around any health claims by replacing fewer desirable ingredients with label-friendly ingredients.

Sensory and Shelf Life

Our prototype meets your sensory within the sphere of physical and scientific possibility by using a unique combination of ingredients without negatively affecting their colour, taste, texture and shelf life.

Regulatory

A prototype that meets the regulatory requirement that governs food processing, including those established by local and international regulations (e.g., FDA and EU regulations )

Science-Based Nutrition

An evidence-based prototype that is specifically built based on science to meet the targeted consumer's needs. In this case, the development of skin whitening and depigmentation products demands the inhibition of tyrosinase and melanosome transfer.

1. • Our team of nutritionists and biomedical and food scientists are working together to discover new bioactive molecules that have increased potency and therapeutic effects on depigmentation and skin lightening.

Keeping this, our formulation scientists develop products rich in antioxidants, including botanicals

1. • Free Radical trapping agents: Glycyrrhizin acid
   • Inhibition of melanosome transfer: Linoleic acid
   • Epidermal turnover accelerant: Liquirtin, salicylic acid, glycolic acid, lactic acid, retinoids, thioctic acid, vitamin E and Vitamin C.
   • Tyrosine inhibition: Hydroquinone, mequinol, arbutin, azelaic acid, kojic acid, ellagic acid, resveratrol, oxyresveratrol,
   • Other foods that prevent acne: Kefir (Probiotic-rich food), moringa, Nettles, dark berries, peppermint, pumpkin seeds, Brazil nut, tomatoes, watercress, water, fennel, oat milk, red grapes, beetroot, tofu, brown rice, legumes, kale, avocado, garlic, alfalfa sprouts, broccoli, artichoke, eggs, burdock, cottage cheese, green tea, sweet potato, acai, mackerel, salmon, oysters, and pumpkin seeds and many more.

We research the functional ingredients to achieve nutritargeting that can go through systemic circulation in active forms, distributed to all skin compartments, including sebum, subcutaneous fat, dermis, and epidermis is more efficient than applying cosmetics.  We work with manufacturers, dermatologists and physicians to test the scientific veracity of the claims.

Forms of delivery

Our team can assist you in developing skin-whitening products in the form of snacks, chocolates, beverages, soups, and gummies, which is a move away from capsules and tablets. We offer nutricosmetics in pill, tablet, gummies, jelly form, sachets forms, and liquid and other food formats.

Health Claim

Functional and Health claims as per the regulatory norms (e.g., no added artificial colours or flavours, and low in sugar)

We adopt a case-by-case approach to design the Treatment of Photomelanosis and Photo Tanning (Nutracosmecutical) product development studies

We comply with Good Manufacturing Practices (GMP) guidelines/

• Discovery of Ingredients or use your commodity to convert as a product
• Nutrient research
• Dosage formulation and strength
• Cosmeceuticals  Product Formulation
• Formula Review/Ingredient Assessment / Product Compliance
• Product-specific Regulatory guidelines/standards
• Shelf stability studies
• Bioavailability research
• Packaging and testing
• Patient compliance
• Dossier report preparation
• Labelling and regulatory compliance
• Label artwork and design
• Novel Food Registration
• Regulatory Intelligence
• Claim consultation and substantiation
• Guidance for Import Regulations in the UK

Guires's scientists and formulation experts identify new delivery mechanisms (such as liposomes) and research-active compounds to develop a highly functional nutraceutical product that provides the intended results. Through years of expertise and knowledge, we bring in the right solutions that fit your requirements.

At Food Research Lab, we give significance to the following aspects of developing a successful functional food product or a Nutracosmeceutical product. Any ingredient incorporated into the formulation needs to achieve its intended function in the human body at the same time, must adhere to safety guidelines. At Guires, we substantiate this from many different types of scientific investigation, including secondary research for existing ingredients or, if its novel, publishing the work in reputable, peer-reviewed journals. Data for this will also be derived from the purity and sustainability of the components (e.g., metal test), chemical comparisons and analysis, activities (e.g., ORAC or oxygen radical absorbance activities), testing in animal models, genomic/gene expression studies, in vitro bioassays and, most compelling of all, human clinical testing. Through years of expertise and knowledge, we bring in the right solutions that fit your requirements.

We follow quality measures to ensure the products are safe from both the supplier's and the buyer's perspectives. We carry out Marker Chemistry (e.g., HPLC, GC etc.), Microbiology tests (e.g., Pseudomonas, Salmonella, Escherichia Coli), heavy metal analysis (e.g., lead, arsenic, cadmium kept below the regulatory limits), Contamination (e.g., metal flakes from machinery), physical characteristics (e.g., powders for tablets must have low moisture content) and stability (e.g., the time for a product from initial production). We use compendium methods (USP and European Pharmacopeia) for an extensive validation process.

We follow a specific set of regulations that a product must adhere to. This includes manufacturing flow chart, solvents, quantitative ingredient lists, physical characteristics, GMO status, certifications, radiations, pesticide/chemical/ residue, contaminants, microbiology, allergens, animal derivation, and safety (Standard Material Safety Data Sheet – toxicity or clinical testing). We ensure to assist in vetting and clearing the ingredient supplier completes clearance through the target country's regulatory agency prior to its inclusion in formulas. Through our years of experience, our team can speed up the acceptance and inclusion of new material. Our product development team complies with the Food, Drug and Cosmetics Act (FDA 2009) and the Fair Packaging and Labeling Act (Federal Trade Commission 2011). Our team ensures to use of only acceptable ingredients that are found in the INCI, International Nomenclature of Cosmetic Ingredients, allocated by the American Cosmetic Association