Inflammation

Food Research Lab provides formulations for food and nutraceutical products specifically related to anti-inflammatory efficacy. We formulate using evidence-supported science, ingredient knowledge, and regulatory insight all used to ensure successful products for market readiness.

There is sufficient evidence to show that glycosaminoglycans or GAGs such as glucosamine sulfate, hyaluronic acid, and chondroitin sulfate (GAIT Intervention Trial Clegg et. al. 2005) play an important role in joint protection. Similarly, ingredients like methylsulfonylmethane (MSM), olive oil, undenatured type II collagen (derived from chicken sternum cartilage), cod liver oil, pomegranate extracts, sulforaphane, conjugated linoleic acid, rose hip extract, avocado/soy unsaponifiables (ASU), Boswellia serrata oleoresin, curcumin, Harpagophytum procumbens (devil’s claw), Kulattha (Macrotyloma uniflorum Lam. / Dolichos biflorus), ginger, moringa, barley, and garlic are among plants that have been studied scientifically and shown to have anti-inflammatory effects.

Well, there are several items presently on the market that have demonstrated success:

• Logic Juice 4 Joints – a juice product that has chondroitin and glucosamine as key ingredients
• Pure Cod Liver Oil supplements
• Joint Care Glucosamine with Chondroitin Plus Fish Oil Omega-3

Formulation experts at Food Research Lab can make custom supplements or products using a single nutrient or a collaborative combination of nutrients with/or without functional additives. These may take the form of a ready-to-mix powder, meal kit, shot, functional beverage, capsule, etc. In addition to your formulation, our group can also assist with pharmaceutical activity, or pharmacokinetic studies to verify efficacy, safety and proper dosing.

• Prototype Development: Developing a prototype that safely meets both the nutritional and sensory needs, utilizing a distinct flavor with natural sweeteners to avoid compromising functional benefits and ensuring it will be accepted by consumers.
• Regulatory Compliance: Developing a prototype that is compliant with regulatory requirements associated with food and nutraceutical processing including FDA, EU regulations, and FSSAI standards.
• Evidence-Based Nutritional Targeting: Developing evidence-based formulations that consider the unique nutritional needs of the targeted consumer population, whether it be joint health, gut health, or anti-inflammatory holistic wellness.
• Nutritionally Focused Innovation: Each product will be tailored to a specific nutritional story - high curcumin bioavailability to support joint health, omega-3 fortification to target cardiovascular inflammation, etc.

• Nutrition Intelligence Services: We apply deep nutrition intelligence to map bioactive ingredients (e.g. Polyphenols, Omega-3 fatty acids, flavonoids, carotenoids, sulfur-containing compounds, probiotics and prebiotics, amino sugars, Glycosaminoglycans GAGs, plant extracts, other bioactive) to specific inflammation pathways, choosing combinations to enhance synergy (e.g. Curcumin + Piperine), identifying overlaps (e.g. Green tea = polyphenols + flavonoids) assuring every formulation that developed by FRL team delivers proven benefits.
• Regulatory Compliance: Our expertise team at FRL also supports regulatory compliance by assisting you meet FSSAI (India), FDA (the USA), and EFSA (Europe) standards by conducting safety and efficacy studies ensuring dosing and regulatory limits and providing health claim substantiation (e.g. Curcumin = proven to reduce inflammatory markers such as IL-6 and CRP in randomized clinical studies) [e.g. Amalraj et al., 2017]; Glucosamine Sulfate (GAIT trial by Clegg et al., 2006) for anti-inflammatory benefits. .
• Ingredient Discovery Services: Besides, formulation (new product development and reverse engineering) and regulatory services, our ingredient research team research and identify novel ingredient through our analytical testing and authentication, pharmacokinetic profiling (assess absorption, metabolism, and efficacy), discovery of novel bioactive synergies (e.g. Curcumin + Piperine, glucosamine + Chondroitin), and literature mining and clinical validation. .
• Ingredient Sourcing Intelligence: In addition, we also partner with our trusted global supply network, assuring the highest quality raw materials with CoA and if demanded clinical trial verification / certification clearance. We offer strong anti-inflammatory ingredients like curcumin, boswellia, resveratrol, and green tea catechins, with CoA (certificate of analyses). .
• Sourcing & Procurement Solutions: Food Research Lab can help with new product innovations, sourcing natural anti-inflammatory ingredients, or you may need assistance with helping you navigate regulatory approvals. Our contract manufacturing services for anti-inflammatory products enable you to scale your formulations into market-ready offerings, from functional beverages and powders to capsules, gummies, and fortified snacks.